[HTML][HTML] Phospholipid flip-flop and phospholipid scramblase 1 (PLSCR1) co-localize to uropod rafts in formylated Met-Leu-Phe-stimulated neutrophils
SC Frasch, PM Henson, K Nagaosa, MB Fessler… - Journal of Biological …, 2004 - ASBMB
Movement of phosphatidylserine (PS) to the plasma membrane outer leaflet is a nearly
universal marker of apoptosis and occurs during activation of many cells. Neutrophils
stimulated with the chemotactic peptide formylated Met-Leu-Phe (fMLP) demonstrated
transient PS exposure. Stimulated outward movement of PS was accompanied by enhanced
inward movement of several phosphorylcholine lipid probes and was associated with
enhanced FM 1-43 staining indicative of phospholipid packing changes. Unlike apoptosis …
universal marker of apoptosis and occurs during activation of many cells. Neutrophils
stimulated with the chemotactic peptide formylated Met-Leu-Phe (fMLP) demonstrated
transient PS exposure. Stimulated outward movement of PS was accompanied by enhanced
inward movement of several phosphorylcholine lipid probes and was associated with
enhanced FM 1-43 staining indicative of phospholipid packing changes. Unlike apoptosis …
