[HTML][HTML] Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands
AG Blunt, A Lawshé, ML Cunningham, ML Seto… - Journal of Biological …, 1997 - ASBMB
FGF-8 is a member of the family of fibroblast growth factors and is expressed during
vertebrate embryo development. Eight potential FGF-8 isoforms are generated by alternative
splicing in mice, several of which are expressed during embryogenesis in epithelial
locations. The significance of the multiple isoforms is currently unknown. In this report, we
investigate the expression patterns and the specificity of the FGF-8 isoforms for known
fibroblast growth factor (FGF) receptors. RNAs for seven of the eight potential isoforms are …
vertebrate embryo development. Eight potential FGF-8 isoforms are generated by alternative
splicing in mice, several of which are expressed during embryogenesis in epithelial
locations. The significance of the multiple isoforms is currently unknown. In this report, we
investigate the expression patterns and the specificity of the FGF-8 isoforms for known
fibroblast growth factor (FGF) receptors. RNAs for seven of the eight potential isoforms are …