Diabetes and the platelet: toward new therapeutic paradigms for diabetic atherothrombosis

O Morel, L Kessler, P Ohlmann, P Bareiss - Atherosclerosis, 2010 - Elsevier
Atherothrombosis–defined as atherosclerotic lesion disruption with superimposed thrombus
formation–is a leading cause of death in patients with diabetes mellitus. Platelets play a
pivotal role in atherothrombosis and platelets of diabetic patients are hyperreactive.
Numerous studies have investigated the usefulness of antiplatelet therapy for primary and
secondary prevention of atherothrombotic events in diabetic patients. However, there are
limited evidences that aspirin may be effective in the reduction of atherothrombotic …