[PDF][PDF] The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability

B Yang, BMM Zwaans, M Eckersdorff, DB Lombard - Cell cycle, 2009 - Taylor & Francis
The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability Page 1 [Cell
Cycle 8:16, 2662-2663; 15 August 2009]; ©2009 Landes Bioscience 2662 Cell Cycle 2009; Vol.
8 Issue 16 Sirtuin deacetylases promote longevity in invertebrates. Mammals possess seven
sirtuin homologs, which are involved in a diverse array of processes including development,
metabolism and stress resistance.Among these, the sirtuin SIRT6 plays a particularly
important role in the maintenance of cellular and organismal homeostasis. Mouse embryonic …