Gut motility disorders represent a significant challenge in clinical management with current
palliative approaches failing to overcome disease and treatment-related morbidity. The
recent progress with stem cells to restore missing or defective elements of the gut
neuromusculature offers new hope for potential cure. Focusing on enteric neuropathies such
as Hirschsprung's disease, the review discusses the progress that has been made in the
sourcing of putative stem cells and the studies into their biology and therapeutic potential. It …