Reasons to consider earlier treatment of chronic HBV infections
F Zoulim, WS Mason - Gut, 2012 - gut.bmj.com
F Zoulim, WS Mason
Gut, 2012•gut.bmj.comBackground Chronic HBV infection is typically divided into four sequential phases 8 9:(1) an
immunotolerance phase lasting two or three decades or more;(2) an immunoreactive phase
with bouts of hepatitis over a period of months or years as the immune system attempts to
clear the infection;(3) a low replicative phase in which very little virus is found in the serum
(usually< 10 4 copies per ml or< 2000 IU/ml) or liver, and the disease is generally inactive
10;(4) sometimes a re-activation phase, in which virus titres rebound along with immune …
immunotolerance phase lasting two or three decades or more;(2) an immunoreactive phase
with bouts of hepatitis over a period of months or years as the immune system attempts to
clear the infection;(3) a low replicative phase in which very little virus is found in the serum
(usually< 10 4 copies per ml or< 2000 IU/ml) or liver, and the disease is generally inactive
10;(4) sometimes a re-activation phase, in which virus titres rebound along with immune …
Background
Chronic HBV infection is typically divided into four sequential phases 8 9:(1) an immunotolerance phase lasting two or three decades or more;(2) an immunoreactive phase with bouts of hepatitis over a period of months or years as the immune system attempts to clear the infection;(3) a low replicative phase in which very little virus is found in the serum (usually< 10 4 copies per ml or< 2000 IU/ml) or liver, and the disease is generally inactive 10;(4) sometimes a re-activation phase, in which virus titres rebound along with immune-mediated liver disease.
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