[HTML][HTML] Endoplasmic reticulum stress induces CAP2 expression promoting epithelial-mesenchymal transition in liver cancer cells
S Yoon, B Shin, HG Woo - Molecules and cells, 2021 - Elsevier
Cyclase-associated protein 2 (CAP2) has been addressed as a candidate biomarker in
various cancer types. Previously, we have shown that CAP2 is expressed during multi-step
hepatocarcinogenesis; however, its underlying mechanisms in liver cancer cells are not fully
elucidated yet. Here, we demonstrated that endoplasmic reticulum (ER) stress induced
CAP2 expression, and which promoted migration and invasion of liver cancer cells. We also
found that the ER stress-induced CAP2 expression is mediated through activation of protein …
various cancer types. Previously, we have shown that CAP2 is expressed during multi-step
hepatocarcinogenesis; however, its underlying mechanisms in liver cancer cells are not fully
elucidated yet. Here, we demonstrated that endoplasmic reticulum (ER) stress induced
CAP2 expression, and which promoted migration and invasion of liver cancer cells. We also
found that the ER stress-induced CAP2 expression is mediated through activation of protein …
