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Pivotal role of CEACAM1 protein in the inhibition of activated decidual lymphocyte functions
Gal Markel, … , Simcha Yagel, Ofer Mandelboim
Gal Markel, … , Simcha Yagel, Ofer Mandelboim
Published October 1, 2002
Citation Information: J Clin Invest. 2002;110(7):943-953. https://doi.org/10.1172/JCI15643.
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Categories: Article Aging

Pivotal role of CEACAM1 protein in the inhibition of activated decidual lymphocyte functions

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Abstract

Research Article

Authors

Gal Markel, Dana Wolf, Jacob Hanna, Roi Gazit, Debra Goldman-Wohl, Yuval Lavy, Simcha Yagel, Ofer Mandelboim

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Figure 1

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CEACAM1 staining of decidual lymphocytes. Decidual lymphocytes were isol...
CEACAM1 staining of decidual lymphocytes. Decidual lymphocytes were isolated and quadruple-stained as described in Methods. (a–c) CEACAM1 staining on nonactivated decidual NK cells (a), T cells (b), and NKT cells (c). One representative experiment is shown out of three performed. Decidual lymphocytes were cultured in the presence of IL-2 as described (20) and then screened for CEACAM1 expression with the 5F4 mAb. (d–f) CEACAM1 staining for activated decidual NK clone (d), T clone (e), and NKT clone (f). Similar results were obtained when other lymphocyte clones were used. (g and h) Staining of EVTs for HLA-G and CEACAM1, respectively. Bold lines represent mAb staining and thin lines show background staining.
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